Реакция #60236

Уравнение реакции

N,N′-dimethylethylenediamine

diphenylamine

4-bromoiodobenzene

→

white crystal

Выход 70.2%

4-bromotriphenylamine

Выход 70.2%

Растворители

xylene

Условия реакции

Обработка

1. 1
   Температураrefluxed for 24 hours under argon atmosphere
2. 2
   Фильтрацияthe mixture was filtered
3. 3
   Другоеto remove an insoluble matter
4. 4
   Концентрированиеthe filtrate was concentrated

Методика

N,N′-dimethylethylenediamine 1.76 g was added to diphenylamine 16.9 g, 4-bromoiodobenzene 28.2 g sodium t-butoxide 14.4 g, copper powder 3.81 g and a xylene 100 ml solution, and the mixture was heated and refluxed for 24 hours under argon atmosphere. After cooled down to room temperature, the mixture was filtered to remove an insoluble matter, and the filtrate was concentrated. The residue was refined by silica gel chromatography to obtain 22.7 g of white crystal of 4-bromotriphenylamine.

Источник