Реакция #6011

Уравнение реакции

acetyl chloride

aluminum chloride

dimethylformamide

benzoselenazolinone

→

6-Acetylbenzoselenazolinone

Условия реакции

Обработка

1. 1
   ТемператураAfter cooling
2. 2
   workup.STIRRINGthe mixture is homogenized
3. 3
   ТемператураIt is heated to 70°-80° C. on an oil bath
4. 4
   workup.STIRRINGwith stirring
5. 5
   Температураheating
6. 6
   Температураis maintained at a temperature of 80°-90° C. for a time T of approximately 4 h 30 min
7. 7
   Другоеon crushed ice
8. 8
   Другоеdried
9. 9
   Промывкаwashed with boiling cyclohexane
10. 10
    Другоеrecrystallized in toluene

Методика

12 grams (0.09 mol) of aluminum chloride are introduced into a ground-necked flask. 3.1 cm3 (0.04 mol) of dimethylformamide are added dropwise with stirring. After cooling, two grams (0.01 mol) of benzoselenazolinone are added and the mixture is homogenized. It is heated to 70°-80° C. on an oil bath with stirring, and 0.01 to 0.012 mol of acetyl chloride is then added. heating is maintained at a temperature of 80°-90° C. for a time T of approximately 4 h 30 min. The mixture is hydrolyzed on crushed ice. The product is drained, dried, and washed with boiling cyclohexane and recrystallized in toluene.

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