Реакция #5914

Уравнение реакции

4-Fluoroaniline

potassium carbonate

18-Crown-6

ethylbromoacetate

→

Ethyl N-(4-fluorophenyl)glycine

Растворители

ethanol

ethanol

Условия реакции

Обработка

1. 1
   Температураthe reaction was heated to reflux

Методика

4-Fluoroaniline (5 g), potassium carbonate (3.11 g) and a catalytic amount of 18-Crown-6 were stirred together in 50 ml of ethanol. A solution of ethylbromoacetate (7.52 g) in 25 ml of ethanol was added dropwise and the reaction was heated to reflux.

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