Реакция #58863

Уравнение реакции

K2CO3

pentynol

t-butyldiphenylsilylchloride

Et3N

→

t-butylpent-4-ynyloxy diphenyl silane

Выход 98.0%

Растворители

CH2Cl2

Условия реакции

Обработка

1. 1
   Экстракцияextracted with CH2Cl2
2. 2
   СушкаThe combined extracts are dried over MgSO4
3. 3
   Концентрированиеconcentrated in vacuo
4. 4
   ФильтрацияThe residue is purified by filtration on a silica pad

Методика

A mixture of pentynol (8.0 g, 95 mmol), t-butyldiphenylsilylchloride (28 g, 114 mmol) and Et3N (14 g, 138 mmol) in CH2Cl2 is stirred at room temperature for 16 h, treated with 1M K2CO3 and extracted with CH2Cl2. The combined extracts are dried over MgSO4 and concentrated in vacuo. The residue is purified by filtration on a silica pad to obtain 30 g of t-butylpent-4-ynyloxy diphenyl silane (yield: 98%

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