Реакция #56940

Уравнение реакции

6-[5-bromo-2-(2-methoxy-benzyloxy)-phenyl]-6-chloro-pyrimidin-2-ylamine

4-methyl-phenylamine

→

title compound

Выход 36.0%

6-[5-Bromo-2-(2-methoxy-benzyloxy)-phenyl]-N*4*-p-tolyl-pyrimidine-2,4-diamine

Выход 36.0%

Условия реакции

Методика

Following the method described in Example 4, 6-[5-bromo-2-(2-methoxy-benzyloxy)-phenyl]-6-chloro-pyrimidin-2-ylamine and 4-methyl-phenylamine provided the title compound (36% yield). 1H NMR (CD3OD) δ 3.82 (s, 3H, CH3), 5.25 (s, 2H, CH2), 6.32 (s, 1H, Ar), 6.89-6.98 (m, 2H, Ar), 7.21-7.30 (m, 6H, Ar), 7.59-7.72 (m, 3H, Ar).

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