Реакция #56937

Уравнение реакции

2-[2-amino-6-(4-chloro-phenylamino) pyrimidin-4-yl]-4-bromo-phenol

4-methoxy-benzyl chloride

→

title compound

Выход 50.0%

6-[5-Bromo-2-(4-methoxy-benzyloxy)-phenyl]-N*4*-(4-chloro-phenyl)-pyrimidine-2,4-diamine

Выход 50.0%

Условия реакции

Методика

Following the method described in Example 165, 2-[2-amino-6-(4-chloro-phenylamino) pyrimidin-4-yl]-4-bromo-phenol and 4-methoxy-benzyl chloride provided the title compound (50% yield). 1H NMR (CD3OD) δ 3.76 (s, 3H, CH3), 5.16 (s, 2H, CH2), 6.37 (s, 1H, Ar), 6.89-6.92 (m, 2H, Ar), 7.28-7.30 (m, 3H, Ar), 7.39-7.42 (m, 2H, Ar), 7.69-7.32 (m, 4H, Ar).

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