Реакция #56912

Уравнение реакции

4-chloro-6-(5-chloro-2-methoxy-phenyl)-pyrimidin-2-yl-amine

4,6-dichloro-pyrimidin-2-yl-amine

5-bromo-2-methoxy-phenyl boronic acid

→

4-chloro-6-(5-bromo-2-methoxy-phenyl)-pyrimidin-2-yl-amine

Выход 53.0%

Условия реакции

Методика

Following the method described in Example 4 for the synthesis of 4-chloro-6-(5-chloro-2-methoxy-phenyl)-pyrimidin-2-yl-amine, 4,6-dichloro-pyrimidin-2-yl-amine and 5-bromo-2-methoxy-phenyl boronic acid provided 4-chloro-6-(5-bromo-2-methoxy-phenyl)-pyrimidin-2-yl-amine (53% yield).

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