Реакция #56518

Уравнение реакции

9-hydroxy-1-oxo-1H-naphtho[2,1-b]pyran-2-carboxaldehyde acetate

hydroxylamine hydrochloride

sodium formate

→

9-Hydroxy-1-oxo-1H-naphtho[2,1-b]pyran-2-carbonitrile

Растворители

formic acid

Условия реакции

Обработка

1. 1
   Температураis refluxed for 30 hrs
2. 2
   ДругоеThe product crystallize
3. 3
   Температураon cooling
4. 4
   Фильтрацияis filtered
5. 5
   Промывкаwashed with acetone

Методика

A mixture of 9-hydroxy-1-oxo-1H-naphtho[2,1-b]pyran-2-carboxaldehyde acetate (1 mm), hydroxylamine hydrochloride (1.3 mm) and sodium formate (2 mm) is refluxed for 30 hrs. in formic acid (3 parts). The product crystallize on cooling, is filtered and washed with acetone. The dry crystals are light beige, m.p. 289°-92° C.

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