Реакция #56258

ord-310402dfa2b2420b82f5826c743adfae

Уравнение реакции

CN(C)CCN
dimethylaminoethylamine
CN(C)CCNC(=O)C(O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O
adenosine-5'-carboxylic acid N-(2-dimethylaminoethyl)-amide
→
C=CCNC(=O)C(O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O
Adenosine-5'-carboxylic acid N-allylamide
Выход 84.0%

Реактанты

CN(C)CCN
dimethylaminoethylamine
CN(C)CCNC(=O)C(O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O
adenosine-5'-carboxylic acid N-(2-dimethylaminoethyl)-amide

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

with dimethylaminoethylamine: adenosine-5'-carboxylic acid N-(2-dimethylaminoethyl)-amide; m.p. 136°-138° C.; yield 84% of theory.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US04224438uspto-grants-1980_09