Реакция #56217

ord-c91bd780110d478faf6ee7c6958d7f87

Уравнение реакции

CC(C)C(C(=O)O)c1cc2ccccc2s1
2-(2-benzothienyl)-3-methylbutanoic acid
CC(C)C(C(=O)O)c1cc2cc(Cl)ccc2s1
2-(5-chloro-2-benzothienyl)-3-methylbutanoic acid
OCc1cccc(Cc2ccccc2)n1
(6-benzyl-2-pyridyl)methanol
→
CC(C)C(C(=O)OCc1cccc(Cc2ccccc2)n1)c1cc2ccccc2s1
(6-benzyl-2-pyridyl)methyl 2-(2-benzothienyl)-3-methylbutanoate
CC(C)C(C(=O)OCc1cccc(Cc2ccccc2)n1)c1cc2cc(Cl)ccc2s1
(6-benzyl-2-pyridyl)methyl 2-(5-chloro-2-benzothienyl)-3-methylbutanoate

Реактанты

—
acid chloride
CC(C)C(C(=O)O)c1cc2ccccc2s1
2-(2-benzothienyl)-3-methylbutanoic acid
CC(C)C(C(=O)O)c1cc2cc(Cl)ccc2s1
2-(5-chloro-2-benzothienyl)-3-methylbutanoic acid
OCc1cccc(Cc2ccccc2)n1
(6-benzyl-2-pyridyl)methanol

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

Following the procedure of Example 12, the acid chloride of each of 2-(2-benzothienyl)-3-methylbutanoic acid and 2-(5-chloro-2-benzothienyl)-3-methylbutanoic acid is reacted with (6-benzyl-2-pyridyl)methanol to yield (6-benzyl-2-pyridyl)methyl 2-(2-benzothienyl)-3-methylbutanoate and (6-benzyl-2-pyridyl)methyl 2-(5-chloro-2-benzothienyl)-3-methylbutanoate.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US04224330uspto-grants-1980_09