Реакция #55664

ord-159cb7efc2f84e90b3701ceb6e2e89f7

Уравнение реакции

CSC(SC)=C(C#N)S(=O)(=O)c1ccccc1
1-benzenesulfonyl-1-cyano-2,2-bis(methylthio)ethylene
Cc1nc[nH]c1CSCCN
2-[(4-methyl-1H-imidazol-5-yl)methylthio]ethylamine
→
CSC(NCCSCc1[nH]cnc1C)=C(C#N)S(=O)(=O)c1ccccc1
title product
CSC(NCCSCc1[nH]cnc1C)=C(C#N)S(=O)(=O)c1ccccc1
1-Benzenesulfonyl-1-cyano-2-methylthio-2-{2-[(4-methyl-1H-imidazol-5-yl)methylthio]ethylamino}ethylene

Реактанты

CSC(SC)=C(C#N)S(=O)(=O)c1ccccc1
1-benzenesulfonyl-1-cyano-2,2-bis(methylthio)ethylene
Cc1nc[nH]c1CSCCN
2-[(4-methyl-1H-imidazol-5-yl)methylthio]ethylamine

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Обработка

  1. 1
    Другое3,950,353] are reacted

Методика

Equimolar amounts of 1-benzenesulfonyl-1-cyano-2,2-bis(methylthio)ethylene [prepared according to the procedure described by M. Augustin et al., Z. Chem., 17, 289 (1977)] and 2-[(4-methyl-1H-imidazol-5-yl)methylthio]ethylamine [prepared according to the procedure described in U.S. Pat. No. 3,950,353] are reacted according to the general procedure of Example 6A, and the title product is produced.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US04221737uspto-grants-1980_09