Реакция #554567

Уравнение реакции

Phosphorus oxychloride

dimethylaniline

phenanthridine

→

9-chlorophenanthridine

Выход 96.0%

Растворители

H2O

Условия реакции

Обработка

1. 1
   Температураby refluxing for 3 hours
2. 2
   Экстракцияthe obtained solid was extracted with chloroform
3. 3
   Сушкаby drying with sodium sulfate
4. 4
   ФильтрацияAfter filtration
5. 5
   Другоеthe filtrate was evaporated to dryness under reduced pressure
6. 6
   ДругоеThe obtained solid was purified by column chromatography (eluent: chloroform) (amount: 2.1 g, yield: 96%)

Методика

Phosphorus oxychloride (15 ml) and dimethylaniline (0.63 ml) were added to phenanthridine (2.0 g), followed by refluxing for 3 hours. The solution was poured into H2O to generate a solid, and the obtained solid was extracted with chloroform, followed by drying with sodium sulfate. After filtration, the filtrate was evaporated to dryness under reduced pressure. The obtained solid was purified by column chromatography (eluent: chloroform) (amount: 2.1 g, yield: 96%).

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