Реакция #54784

Уравнение реакции

4-(2,2-diethoxyethyl)-3-(α-methylbenzyl)-5-methylthio-4H-1,2,4-triazole

sulfuric acid

→

11-methyl-3-methylthio-11H-s-triazolo[3,4-b][3]benzazepine

Условия реакции

Обработка

1. 1
   Другоеthe cyclization reaction mixture
2. 2
   workup.ADDITIONwas treated by a procedure similar to

Методика

12.5 g of the 4-(2,2-diethoxyethyl)-3-(α-methylbenzyl)-5-methylthio-4H-1,2,4-triazole prepared in Reference Example 10 was added to cold concentrated sulfuric acid and the cyclization reaction mixture was treated by a procedure similar to that described in Example 2. By the above procedure was obtained 11-methyl-3-methylthio-11H-s-triazolo[3,4-b][3]benzazepine as an oil.

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