Реакция #54555

Уравнение реакции

1-(p-chlorophenyl)-3-amino-2-pyrazoline

pyridine

→

1-(p-chlorophenyl)-3-amino-pyrazole

Выход 51.6%

Растворители

ethanol

Условия реакции

Обработка

1. 1
   ДругоеThe oxidized product was isolated as in Example 2

Методика

In the same apparatus and according to the same modalities as in Example 1, 1.95 g (0.01 mole) of 1-(p-chlorophenyl)-3-amino-2-pyrazoline were suspended in 12 ml of ethanol and 0.1 ml of pyridine with addition of 0.1 g of CuCl, under an oxygen head. Oxidation was completed after about 10 hours. The oxidized product was isolated as in Example 2, thus obtaining 1 g of 1-(p-chlorophenyl)-3-amino-pyrazole of melting point 107°-108° C.

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