Реакция #54238

Уравнение реакции

2-Bromo-3-phenyl-butyrophenone

1,2,4-triazole

potassium carbonate

→

title compound

2-(1,2,4-Triazol-1-yl)-3-phenylbutyrophenone

Растворители

methyl ethyl ketone

Условия реакции

Обработка

1. 1
   Фильтрацияthe solution was filtered
2. 2
   Другоеthe solvent removed in vacuo
3. 3
   ДругоеRecrystallisation of the residue from ethanol/petroleum ether (60°-80°)

Методика

2-Bromo-3-phenyl-butyrophenone (0.02 mol), 1,2,4-triazole (0.02 mol) and potassium carbonate (0.04 mol) were refluxed in methyl ethyl ketone (100 ml) for 36 hours. After cooling to room temperature, the solution was filtered and the solvent removed in vacuo. Recrystallisation of the residue from ethanol/petroleum ether (60°-80°) gave the title compound as a colourless solid, m.p. 166°-8°.

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