Реакция #54170

ord-abc3c1bef80649e3acc4e6b3f41db6cd

Уравнение реакции

CCCCOCCO
2 -Butoxyethanol
CC(=O)CCC(=O)O
levulinic acid
CCCCCCCC(=O)[O][Sn]([CH2]CCC)([CH2]CCC)[O]C(=O)CCCCCCC
dibutyl tin dioctoate
→
CCCCOCCOC(=O)CCC(C)=O
2-Butoxyethyl Levulinate

Реактанты

—
232g
CCCCOCCO
2 -Butoxyethanol
CC(=O)CCC(=O)O
levulinic acid
CCCCCCCC(=O)[O][Sn]([CH2]CCC)([CH2]CCC)[O]C(=O)CCCCCCC
dibutyl tin dioctoate
—
ester
—
349g

Реагенты

Нет

Растворители

Cc1ccccc1C
xylene

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Обработка

  1. 1
    Другоеwhile collecting 42g water
  2. 2
    ПромывкаProduct was washed with sat. NaHCO3 and water
  3. 3
    Другоеdried with anhy
  4. 4
    workup.DISTILLATIONMgSO4 and distilled
  5. 5
    ДругоеEster product was collected in fr 2 and 3 120°-131° 1 mm
  6. 6
    ДругоеYield

Методика

2 -Butoxyethanol (Butyl Cellosolve) 354g (3 mol), 232g (2 mol) levulinic acid and 1.5g dibutyl tin dioctoate were heated with a xylene azeotrope for 24 hours 151°-177° to AN 2.3 while collecting 42g water. Product was washed with sat. NaHCO3 and water, dried with anhy. MgSO4 and distilled. Ester product was collected in fr 2 and 3 120°-131° 1 mm. Yield was 349g, 81%, 96% ester product by gc.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US04147686uspto-grants-1979_04