Реакция #5411

Уравнение реакции

2-ethoxycarbonylimino-3-(3-trifluoromethylphenyl)thiazolidine

N-bromosuccinimide

→

2-ethoxycarbonylimino-3-(3-trifluoromethylphenyl)-5-bromothiazoline

Выход 45.3%

Растворители

chloroform

Условия реакции

Обработка

1. 1
   ТемператураAfter cooling
2. 2
   Промывкаthe reaction mixture was washed with an aqueous sodium sulfite solution
3. 3
   Сушкаdried over anhydrous magnesium sulfate
4. 4
   ДругоеThe solvent was removed under reduced pressure

Методика

A solution of 2-ethoxycarbonylimino-3-(3-trifluoromethylphenyl)thiazolidine (1.6 g) and N-bromosuccinimide (2 g) in chloroform (50 ml) was refluxed for 10 hours. After cooling, the reaction mixture was washed with an aqueous sodium sulfite solution and dried over anhydrous magnesium sulfate. The solvent was removed under reduced pressure, and the residue was subjected to column chromatography to give 0.9 g of 2-ethoxycarbonylimino-3-(3-trifluoromethylphenyl)-5-bromothiazoline (Compound No. 30).

Источник