Реакция #536923

Уравнение реакции

1b

3-[(3-Amino-4-methylamino-benzoyl)-phenyl-amino]propionic acid methyl ester

N-(4-cyano-phenyl)-glycine

CDI

→

3-({3-[2-(4-Cyano-phenylamino)-acetylamino]-4-methylamino-benzoyl}-phenylamino)-propionic acid methyl ester

Растворители

THF

Условия реакции

Обработка

1. 1
   ДругоеAfter completion of the reaction the mixture
2. 2
   Другоеwas evaporated to dryness
3. 3
   Другоеthe crude product was used without further purification

Методика

The product of 1b (23.2 mmol) and N-(4-cyano-phenyl)-glycine (23.2 mmol) were coupled with CDI (23.2 mmol) in dry THF at room temperature. After completion of the reaction the mixture was evaporated to dryness and the crude product was used without further purification.

Источник