Реакция #53078

ord-3d9852db331a4c56a82063a7cc1d760e

Уравнение реакции

COC(=C1C(=O)N(C(C)=O)c2ccc([N+](=O)[O-])cc21)c1ccccc1
1-acetyl-3-(1-methoxy-1-phenyl-methylidene)-5-nitro-2-indolinone
Nc1ccc(N2CCOCC2)cc1
4-morpholinoaniline
N
ammonia
→
O=C1Nc2ccc([N+](=O)[O-])cc2/C1=C(/Nc1ccc(N2CCOCC2)cc1)c1ccccc1
(Z)-3-[1-(4-morpholinophenylamino)-1-phenyl-methylidene]-5-nitro-2-indolinone

Реактанты

COC(=C1C(=O)N(C(C)=O)c2ccc([N+](=O)[O-])cc21)c1ccccc1
1-acetyl-3-(1-methoxy-1-phenyl-methylidene)-5-nitro-2-indolinone
Nc1ccc(N2CCOCC2)cc1
4-morpholinoaniline
N
ammonia

Реагенты

Нет

Растворители

ClCCl
dichloromethane

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

Prepared analogously to Example 77 from 1-acetyl-3-(1-methoxy-1-phenyl-methylidene)-5-nitro-2-indolinone and 4-morpholinoaniline in dichloromethane and subsequent treatment with methanolic ammonia.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US06855710B2uspto-grants-2005_02