Реакция #53008

ord-318a4454c4ab4a2498939cde2b72a4cc

Уравнение реакции

CC(=O)N1C(=O)C(=C(Cl)c2ccccc2)c2ccccc21
1-acetyl-3-(1-chloro-1-phenyl-methylidene)-2-indolinone
COc1cccc(N)c1
3-methoxyaniline
[Na+].[OH-]
sodium hydroxide
→
COc1cccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)c1
(Z)-3-[1-(3-methoxy-phenylamino)-1-phenyl-methylidene]-2-indolinone

Реактанты

CC(=O)N1C(=O)C(=C(Cl)c2ccccc2)c2ccccc21
1-acetyl-3-(1-chloro-1-phenyl-methylidene)-2-indolinone
COc1cccc(N)c1
3-methoxyaniline
[Na+].[OH-]
sodium hydroxide

Реагенты

Нет

Растворители

C1CCOC1
THF

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

Prepared analogously to Example 2 from 1-acetyl-3-(1-chloro-1-phenyl-methylidene)-2-indolinone and 3-methoxyaniline in THF and subsequent treatment with sodium hydroxide solution.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US06855710B2uspto-grants-2005_02