Реакция #52585

Уравнение реакции

5-Fluoroisatin

→

title compound

5-Fluoro-2-oxindole

Растворители

hydrazine hydrate

—

ice water

Условия реакции

Обработка

1. 1
   Температураrefluxed for 1.0 hr
2. 2
   ДругоеThe reaction mixtures
3. 3
   ФильтрацияThe precipitate was then filtered
4. 4
   Промывкаwashed with water
5. 5
   Другоеdried in a vacuum oven

Методика

5-Fluoroisatin (8.2 g) was dissolved in 50 mL of hydrazine hydrate and refluxed for 1.0 hr. The reaction mixtures were then poured in ice water. The precipitate was then filtered, washed with water and dried in a vacuum oven to afford the title compound.

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