Реакция #52203

Уравнение реакции

2,4-Dichlorobenzenesulphonyl chloride

1-propylamine

→

title compound

2,4-Dichloro-1-(1-propylsulphamoyl)benzene

Растворители

n-butanol

Условия реакции

Обработка

1. 1
   Температураat reflux for 48 hour
2. 2
   ДругоеThe volatiles were removed by evaporation
3. 3
   Другоеthe residue triturated with ether
4. 4
   Фильтрацияthe product collected by filtration

Методика

2,4-Dichlorobenzenesulphonyl chloride (500 mg 2.1 mmol) and 1-propylamine (0.2 ml, 2.4 mmol) in n-butanol (10 ml) was heated at reflux for 48 hour. The volatiles were removed by evaporation and the residue triturated with ether and the product collected by filtration to give the title compound. NMR: 0.78 (t, 3H), 1.35 (q, 2H), 2.79 (t, 2H), 7.60 (dd, 1H), 7.84 (d, 1H), 7.92 (d, 2H)

Источник