Реакция #52043

Уравнение реакции

4-chloro-3-nitro-quinoline

isobutyl amine

triethylamine

→

4-isobutyl-3-nitro quinoline

Растворители

toluene

Условия реакции

Обработка

1. 1
   ПромывкаAfter washing
2. 2
   Другоеphase separation

Методика

4-chloro-3-nitro-quinoline is reacted with isobutyl amine in the presence of triethylamine (TEA) at between −10 and +15° C. in toluene, while excluding moisture. After washing and phase separation, the organic solution is ready for the next step.

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