Реакция #518098

Уравнение реакции

piperazine

9-anthacenemethanol

pyridine

p-nitrophenyl chloroformate

→

9-anthracenylmethyl-1-piperazinecarboxylate

Растворители

water

Условия реакции

Обработка

1. 1
   ДругоеProduct is isolated
2. 2
   Другоеto provide a crude anthrylmethyl p-nitrophenyl carbonate, which
3. 3
   Экстракцияextracted with a solvent
4. 4
   ПромывкаThe product is washed
5. 5
   Другоеdried

Методика

PAC is produced by adding 9-anthacenemethanol and pyridine to a solution of p-nitrophenyl chloroformate. Product is isolated to provide a crude anthrylmethyl p-nitrophenyl carbonate, which is then added to a solution of piperazine. The reacted mixture is poured into water and extracted with a solvent, preferably an organic solvent such as toluene. The product is washed and dried to provide 9-anthracenylmethyl-1-piperazinecarboxylate (PAC).

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