Реакция #51276

Уравнение реакции

4-bromophenol

isobutylene

→

2-tert-butyl-4-bromophenol

Условия реакции

Обработка

1. 1
   Другоеis passed through for 30 hours
2. 2
   ТемператураThe reaction mixture is cooled
3. 3
   Другоеthe residue is purified
4. 4
   Промывкаeluted with a mixture
5. 5
   Другое88.00 g (90%) of the expected compound are collected in the form of a yellow oil

Методика

80.00 g (426.0 mmol) of 4-bromophenol and 8.00 g of Dowex 50WX8 sulphonic acid resin are mixed in a 250 ml three-necked flask. The mixture is heated to 80° C. and a stream of isobutylene is passed through for 30 hours. The reaction mixture is cooled and the residue is purified by passing through a silica column eluted with a mixture composed of 95% dichloromethane and of 5% heptane. 88.00 g (90%) of the expected compound are collected in the form of a yellow oil.

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