Реакция #51269

Уравнение реакции

1-bromo-3-methyl-2-butene

2-bromothiophenol

DMF

potassium carbonate

→

2-bromo-1-(3-methylbut-2-enylthio)benzene

Растворители

water

Условия реакции

Обработка

1. 1
   Экстракцияextracted with ethyl acetate
2. 2
   Другоеthe organic phase is separated
3. 3
   Промывкаwashed with water
4. 4
   Сушкаdried over magnesium sulphate
5. 5
   Другоеevaporated
6. 6
   Другое26.00 g (99%) of the expected compound are collected in the form of an orangey oil

Методика

19.30 g (102.0 mmol) of 2-bromothiophenol, 160 ml of DMF and 15.50 g (112.0 mmol) of potassium carbonate are introduced into a three-necked flask. 13 ml (112.0 mmol) of 1-bromo-3-methyl-2-butene are added dropwise and the reaction mixture is stirred at room temperature for two hours. It is poured into water and extracted with ethyl acetate and the organic phase is separated by settling, washed with water, dried over magnesium sulphate and evaporated. 26.00 g (99%) of the expected compound are collected in the form of an orangey oil.

Источник