Реакция #50652

Уравнение реакции

2-methyl-1-undecene

parabromphenol

→

4-bromo-2-(1,1-dimethyldecyl)-phenol

Условия реакции

Обработка

1. 1
   Промывкаpreviously washed with water
2. 2
   Промывкаrinsed with acetone and oven
3. 3
   Другоеdried for 3 hours at 80° C.
4. 4
   Температураis heated at 100°-110° C. for 48 hours
5. 5
   Другоеchromatographed on a silica column (eluant
6. 6
   workup.ADDITIONa mixture of dichloromethane, 40% and hexane, 60%),

Методика

A mixture of 2-methyl-1-undecene (35.6 g, 211 mmoles), parabromphenol (36.6 g, 211 mmoles) and Dowex 50×12 resin (100-200 mesh) previously washed with water, rinsed with acetone and oven dried for 3 hours at 80° C., is heated at 100°-110° C. for 48 hours. The mixture is then cooled to ambient temperature and chromatographed on a silica column (eluant: a mixture of dichloromethane, 40% and hexane, 60%), yielding 4-bromo-2-(1,1-dimethyldecyl)-phenol in the form of a pale yellow oil. (30.85 g, 43%).

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