Реакция #502097

Уравнение реакции

sodium borohydride

5-[2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]furan-2-carbaldehyde

→

compound

Выход 37.3%

{5-[2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-6-yl]furan-2-yl}methanol

Выход 37.3%

Растворители

methanol

Условия реакции

Обработка

1. 1
   Другоеthe solvent is then evaporated off under reduced pressure
2. 2
   ДругоеThe organic phase is separated
3. 3
   Сушкаdried over sodium sulphate
4. 4
   Концентрированиеconcentrated under reduced pressure

Методика

122 mg of sodium borohydride are added, in small portions, to 104 mg of 5-[2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]furan-2-carbaldehyde dissolved in 20 ml of methanol. The mixture is subsequently stirred at ambient temperature for 2 hours, and the solvent is then evaporated off under reduced pressure. The residue is taken up between dichloromethane and water. The organic phase is separated, dried over sodium sulphate and concentrated under reduced pressure. 39 mg of compound are obtained.

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