Реакция #502074

Уравнение реакции

(2S)-6-methylhept-5-en-2-ol

→

(2S)-6-methylheptan-2-ol

Растворители

methanol

Условия реакции

Обработка

1. 1
   Другоеfitted with a magnetic stirrer
2. 2
   ДругоеThe flask was evacuated
3. 3
   ДругоеThe crude reaction mixture
4. 4
   Фильтрацияwas filtered
5. 5
   Другоеthe solvent removed in vacuo

Методика

5% Palladium on carbon (0.02 g), (2S)-6-methylhept-5-en-2-ol (4.0 g, 3 mmol) and methanol (20 mL) were added to a 50 mL round-bottomed flask fitted with a magnetic stirrer. The flask was evacuated and then pressurised with 1 bar of hydrogen from a balloon. This was repeated three times then the reaction mixture was stirred for 8 hours at room temperature under hydrogen. The crude reaction mixture was filtered and the solvent removed in vacuo to yield (2S)-6-methylheptan-2-ol (3.4 g, 26 mmol, chemical yield 85%), suitable for the next stage.

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