Реакция #48975

Уравнение реакции

dimethylamine

1,8-dibromooctane

4-(3,5-dichloropyridin-4-ylamino)-8-hydroxy-7-methoxy-2H-chromen-2-one

→

title compound

4-(3,5-Dichloropyridin-4-ylamino)-8-(8-(dimethylamino)octyloxy)-7-methoxy-2H-chromen-2-one

Условия реакции

Методика

The title compound was prepared from dimethylamine, 1,8-dibromooctane, and 4-(3,5-dichloropyridin-4-ylamino)-8-hydroxy-7-methoxy-2H-chromen-2-one (Example 29) following the procedures outlined in Examples 25 & 27. 1H NMR (400 MHz, DMSO-d6): δ 9.38 (br s, 1H), 8.59 (s, 2H), 7.85 (d, 1H), 7.05 (d, 1H), 4.26 (br s, 1H), 3.95 (t, 2H), 3.87 (s, 3H), 2.50 (br, 2H), 2.34 (s, 6H), 1.67 (m, 2H), 1.45 (m, 4H), 1.28 (m, 6H); MS (ESI): 508.0.

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