Реакция #487510

Уравнение реакции

dichlorodiphenyl methane

N,N-dimethylformamide

benzophenone

thionyl chloride

→

dichlorodiphenyl methane toluene

Растворители

toluene

water

Условия реакции

Обработка

1. 1
   Другоеa reaction at a reaction temperature of 75° C. for 12 hours
2. 2
   workup.ADDITIONwere added
3. 3
   Температураunder ice-cooling
4. 4
   Другоеliquid separation
5. 5
   Другоеremove the aqueous layer

Методика

25.6 mL of N,N-dimethylformamide (DMF) (manufactured by Wako Pure Chemical Industries Ltd.) was added to 60.1 g of benzophenone (manufactured by Wako Pure Chemical Industries Ltd., and then 60.2 mL of thionyl chloride (manufactured by Wako Pure Chemical Industries Ltd.) was added dropwise thereto, followed by performing a reaction at a reaction temperature of 75° C. for 12 hours. After confirming the production of the dichlorodiphenyl methane by means of 1H-NMR, 60 mL of toluene and 80 mL of water were added thereto under ice-cooling to perform liquid separation and remove the aqueous layer, thereby obtaining a dichlorodiphenyl methane/toluene solution.

Источник