Реакция #48609

Уравнение реакции

3,3-dimethylbutan-1-ol

vinyl acetate

sodium carbonate

→

title compound

3,3-Dimethyl-1-vinyloxybutane

Растворители

benzene

Условия реакции

Обработка

1. 1
   Другое12 hours
2. 2
   Фильтрацияfilter
3. 3
   workup.DISTILLATIONDistill the filtrate
4. 4
   Другоеcollect fraction
5. 5
   Другоеboiling ˜125° C.-130° C
6. 6
   ДругоеFlush through a silica gel pad with hexanes
7. 7
   Концентрированиеconcentrate

Методика

Add chloro(1,5-cyclooctadiene)iridium(I) dimer (0.39 g, 0.59 mmol) to 3,3-dimethylbutan-1-ol (3.00 g, 29.35 mmol), vinyl acetate (10.11 g, 117.42 mmol) and sodium carbonate (1.87 g, 17.61 mmol) in benzene (10 mL) at room temperature. Boil under nitrogen 12 hours. Cool to room temperature and filter. Distill the filtrate and collect fraction boiling ˜125° C.-130° C. Flush through a silica gel pad with hexanes and concentrate to provide the title compound.

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