Реакция #4855

Уравнение реакции

2,3-dihydro-5,7-dinitro-2-methyl-benzofuran

methylamine

→

1-(2-methylamino-3,5-dinitrophenyl)-2-propanol

Растворители

ethanol

Условия реакции

Обработка

1. 1
   ТемператураAfter the mixture is cooled
2. 2
   Другоеthe expected product precipitates
3. 3
   Промывкаwashed with alcohol
4. 4
   Другоеrecrystallized from 50 ml of 96° strength ethanol
5. 5
   ДругоеAfter being dried
6. 6
   Другое0.047 mole (12 g) is obtained of a product which melts at 132° C.

Методика

0.056 Mole (12.5 g) of 2,3-dihydro-5,7-dinitro-2-methyl-benzofuran is suspended in 100 ml of a 33% strength solution of methylamine in ethanol. After 10 hours' stirring at room temperature in a sealed Erlenmeyer, the reaction mixture is brought for 30 minutes to the refluxing temperature of the alcohol. After the mixture is cooled, the expected product precipitates. It is drained, washed with alcohol and then recrystallized from 50 ml of 96° strength ethanol. After being dried, 0.047 mole (12 g) is obtained of a product which melts at 132° C.

Источник