Реакция #475712

Уравнение реакции

isobutyric acid

tetramethylammonium hydroxide

→

product ( 1b )

Tetramethylammonium isobutyrate

Условия реакции

Обработка

1. 1
   ДругоеThe water was removed under reduced pressure
2. 2
   Другоеazeotroped with toluene (2×2 L)

Методика

To a 20 L, round bottom flask was added isobutyric acid (1300 mL, 14 mol), and an aqueous solution of 25% tetramethylammonium hydroxide (5 L, 14 mol). The water was removed under reduced pressure, and azeotroped with toluene (2×2 L) to leave the product (1b) as an amber liquid, which was used without further purification.

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