Реакция #4712

Уравнение реакции

methylisothiocyanate

N-[3-[3-(1-piperidinylmethyl) phenoxy]propyl]-hydrazine carboxamide

→

2-(Methylaminothioxomethyl)-N-[3-[3-(1-piperidinylmethyl)phenoxy]-propyl]-hydrazine carboxamide

Растворители

THF

Условия реакции

Обработка

1. 1
   ДругоеThe precipitate obtained
2. 2
   Фильтрацияis filtered off
3. 3
   Другоеrecrystallised from ethanol

Методика

0.5 g (6.6 mmol) of methylisothiocyanate are added to 1.0 g (3.3 mmol) of N-[3-[3-(1-piperidinylmethyl) phenoxy]propyl]-hydrazine carboxamide in 20 ml of THF and the mixture is stirred at room temperature for 12 hours. The precipitate obtained is filtered off and recrystallised from ethanol. The analytical values are summarized in Table I.

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