Реакция #470366

Уравнение реакции

potassium fluoride

N-methoxymethyl-N-methylpyrrolidinium perchlorate

→

desired product

N-Methoxymethyl-N-Methylpyrrolidinium Fluoride

Растворители

water

Условия реакции

Обработка

1. 1
   ДругоеThe mixture was reacted at room temperature for 1.5 hours
2. 2
   Другоеwhereby the reaction was terminated
3. 3
   workup.ADDITIONWith addition of 100 ml of methanol
4. 4
   Фильтрацияthe reaction mixture was filtered
5. 5
   КонцентрированиеThe filtrate was concentrated
6. 6
   Другоеdried in a vacuum
7. 7
   workup.DISSOLUTIONThe residue was then dissolved in dichloromethane
8. 8
   Фильтрацияthe solution was again filtered with a membrane
9. 9
   Фильтрацияfilter
10. 10
    Концентрированиеthe filtrate was concentrated
11. 11
    Другоеdried

Методика

A 0.44 g quantity of potassium fluoride (product of Wako Pure Chemical Ind. Ltd.) was dissolved in 11 g of deionized water, and 1.74 g of N-methoxymethyl-N-methylpyrrolidinium perchlorate was added to the solution. The mixture was reacted at room temperature for 1.5 hours, whereby the reaction was terminated. With addition of 100 ml of methanol, the reaction mixture was filtered. The filtrate was concentrated and dried in a vacuum. The residue was then dissolved in dichloromethane, the solution was again filtered with a membrane filter, and the filtrate was concentrated and dried, giving 1.05 g of the desired product.

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