Реакция #462968

Уравнение реакции

potassium hydroxide

2-hydroxybenzenesulfonamide

chlorotrifluoroethylene

→

title compound

Выход 60.7%

2-(2-Chloro-1,1,2-trifluoroethoxy)-benzenesulfonamide

Выход 60.7%

Растворители

acetone

Условия реакции

Обработка

1. 1
   workup.STIRRINGAt 40° to 50° C. and while stirring
2. 2
   Другоеwas gassed in over a period of 12 hours
3. 3
   ФильтрацияThe precipitate was filtered off under such and
4. 4
   Промывкаwashed with acetone
5. 5
   ДругоеThe filtrate was evaporated down under reduced pressure
6. 6
   workup.STIRRINGstirred into 700 ml of water, suction
7. 7
   Фильтрацияfiltered
8. 8
   Промывкаwashed
9. 9
   Другоеdried

Методика

At 25 bis 30° C. and while stirring, 5.9 g (0.093 mol) of 88% strength potassium hydroxide powder was added over a period of 5 minutes to a solution of 28.4 g (0.164 Mol) of 2-hydroxybenzenesulfonamide in 200 ml of acetone. At 40° to 50° C. and while stirring, 29.6 g (0.254 mol) of chlorotrifluoroethylene was gassed in over a period of 12 hours. The precipitate was filtered off under such and washed with acetone. The filtrate was evaporated down under reduced pressure, stirred into 700 ml of water, suction filtered, washed and dried. There was obtained 28.8 g (60.7%) of the title compound of m.p. 113° to 116° C.

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