Реакция #46043

Уравнение реакции

(αS)-α-[[(1,1-dimethylethoxy)carbonyl]-amino]-3-hydroxytricyclo[3.3.1.13,7]decane-1-acetic acid

3-hydroxy-α-oxotricyclo[3.3.1.13,7]-decane-1-acetic acid

→

(αS)-α-amino-3-hydroxytricyclo[3.3.1.13,7]decane-1-acetic acid

Условия реакции

Обработка

1. 1
   Другоеto prepare

Методика

U.S. application Ser. No. 10/716,012 filed Nov. 18, 2003 discloses a method for preparing (αS)-α-[[(1,1-dimethylethoxy)carbonyl]-amino]-3-hydroxytricyclo[3.3.1.13,7]decane-1-acetic acid which utilizes 3-hydroxy-α-oxotricyclo[3.3.1.13,7]-decane-1-acetic acid as a starting material and wherein an enzymatic reductive amination is used to prepare and isolate (αS)-α-amino-3-hydroxytricyclo[3.3.1.13,7]decane-1-acetic acid which is converted to the desired product in a separate step.

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