Реакция #452424

Уравнение реакции

N-(4-fluorobenzoyl)-4-nitroaniline

→

N-(4-fluoro-benzoyl)-4-aminoaniline

Выход 79.0%

Растворители

tetrahydrofuran

Условия реакции

Обработка

1. 1
   ФильтрацияThe reaction mixture was then filtered
2. 2
   Концентрированиеthe filtrate concentrated under reduced pressure

Методика

A mixture of 32.25 gm (124 mMol) N-(4-fluorobenzoyl)-4-nitroaniline and 3.2 gm platinum on carbon in 500 mL tetrahydrofuran was hydrogenated at room temperature for 18 hours with an initial pressure of 60 p.s.i. The reaction mixture was then filtered and the filtrate concentrated under reduced pressure to give 22.45 gm (79%) of N-(4-fluoro-benzoyl)-4-aminoaniline.

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