Реакция #452414

Уравнение реакции

n-butyl bromide

NaHCO3

m-aminophenol

→

3-(n-butylamino)phenol

Выход 57.0%

Растворители

methanol

Условия реакции

Обработка

1. 1
   Температураthe mixture is refluxed for 5 h
2. 2
   ТемператураAfter cooling
3. 3
   Фильтрацияit is filtered
4. 4
   Другоеthe solvent is removed in vacuo

Методика

0.11 mol of n-butyl bromide and 0.1 mol NaHCO3 are added to 0.1 mol of m-aminophenol in 150 ml of methanol, and the mixture is refluxed for 5 h. After cooling, it is filtered and the solvent is removed in vacuo. The oil which remains is fractionated in vacuo, to give 3-(n-butylamino)phenol.

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