Реакция #44943

Уравнение реакции

mupirocin calcium

Water

mupirocin calcium

→

Mupirocin Calcium Dihydrate

Растворители

methanol

Условия реакции

Обработка

1. 1
   Другоеto give a clear solution
2. 2
   ДругоеMethanol from the solution was evaporated at reduced pressure
3. 3
   Другоеto give a final volume of 7 ml
4. 4
   Другоеto crystallize for 60 h at 5° C
5. 5
   ФильтрацияThe crystalline product was filtered
6. 6
   Промывкаwashed with water (5 ml)
7. 7
   ДругоеThe product was dried at 30° C. for 12 h.

Методика

Amorphous mupirocin calcium (5.00 g, 4.80 mmole) was dissolved in methanol (15 ml) and stirred to give a clear solution. Water (10 ml) was added to the solution. Methanol from the solution was evaporated at reduced pressure to give a final volume of 7 ml. The mupirocin calcium solution was allowed to crystallize for 60 h at 5° C. The crystalline product was filtered and washed with water (5 ml). The product was dried at 30° C. for 12 h.

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