Реакция #4473

Уравнение реакции

product

1,3-Cyclohexanedione mono(4-bromophenylhydrazone)

water

→

title compound

6-Bromo-1,2,3,9-tetrahydro-4H-carbazol-4-one

Растворители

acetic acid

Условия реакции

Обработка

1. 1
   ТемператураThe mixture was cooled
2. 2
   Фильтрацияthe resulting solid filtered off
3. 3
   Другоеdried (0.95 g)
4. 4
   ДругоеPurification by flash chromatography (E)

Методика

The product of Stage (i) (1.5 g) was heated under reflux with dry zinc chloride (16 g) in glacial acetic acid (75 ml) for 24 h. The mixture was cooled, poured into water (200 ml), and the resulting solid filtered off and dried (0.95 g). Purification by flash chromatography (E) gave the title compound as a solid (125 mg). T.l.c. (F), Rf 0.65

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