Реакция #445808

Уравнение реакции

1,8-dibromooctane

ethylisobutyrate

lithium diisopropylamide

→

title compound

Выход 16.5%

Ethyl 2,2-Dimethyl-10-bromodecanoate

Выход 16.5%

Растворители

hexamethylphosphoramide

Условия реакции

Методика

Using the method described in Example 5(i), 1,8-dibromooctane (27.2 g, 0.1 mol) and ethylisobutyrate (10.44 g, 0.09 mol) were reacted in the presence of lithium diisopropylamide (67 ml, 0.1 mol) and hexamethylphosphoramide (22 g) to give the title compound (4.56 g) as an oil.

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