Реакция #44395

ord-dc25e8728ed9419292ce3c6842ce86a5

Уравнение реакции

O=C(O)c1ccc(Br)cc1F
4-bromo-2-fluorobenzoic acid
CN.Cl
methylamine hydrochloride
→
CNC(=O)c1ccc(Br)cc1F
sub-title compound
CNC(=O)c1ccc(Br)cc1F
4-bromo-2-fluoro-N-methyl-benzamide

Реактанты

O=C(O)c1ccc(Br)cc1F
4-bromo-2-fluorobenzoic acid
CN.Cl
methylamine hydrochloride

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

The sub-title compound was prepared by the method of example 18 step a) using 4-bromo-2-fluorobenzoic acid and methylamine hydrochloride.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US07737135B2uspto-grants-2010_06