Реакция #44347

Уравнение реакции

diethyl ether

water

product

[4-(methylthio)-3-(trifluoromethyl)phenyl]-boronic acid

pinacol

→

4,4,5,5-tetramethyl-2-[4-(methylthio)-3-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane

Растворители

dioxan

Условия реакции

Обработка

1. 1
   ДругоеThe organic layer was separated
2. 2
   Промывкаwashed with brine
3. 3
   Сушкаdried (Na2SO4)
4. 4
   Концентрированиеconcentrated in vacuo

Методика

The product of step b) (0.25 g) was heated in dioxan (2 ml) with pinacol (2 equiv) for 3 h. The solution was treated with diethyl ether and water. The organic layer was separated, washed with brine, dried (Na2SO4) and concentrated in vacuo. Yield 85 mg.

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