Реакция #436335

Уравнение реакции

1-naphthalenone

→

(1S)-1,2,3,4-tetrahydro-1-naphthalenol

Растворители

water

Условия реакции

Обработка

1. 1
   ПромывкаWashed phaseolus aureus L (green grams) 50 g
2. 2
   Другоеwere taken into a conical flask
3. 3
   workup.WAITto shake for 46 hr at 15–20° C
4. 4
   ФильтрацияThen the green grams were filtered off
5. 5
   Промывкаwashed with deionised water (3×100 ml)
6. 6
   ЭкстракцияThe combined filtrate was extracted with chloroform (3×500 ml)
7. 7
   СушкаThe chloroform layer was dried
8. 8
   Другоеthe crude product obtained (480 mg)

Методика

Washed phaseolus aureus L (green grams) 50 g. were taken into a conical flask and allowed to soak in deionised water (400 ml) for a period of 24 hr. 1-naphthalenone (0.500 g; 0.0034 moles) III was added to the soaked phaseolus aureus L (green grams) in the above water, covered and allowed to shake for 46 hr at 15–20° C. Then the green grams were filtered off and washed with deionised water (3×100 ml). The combined filtrate was extracted with chloroform (3×500 ml). The chloroform layer was dried and the crude product obtained (480 mg). Pure (1S)-1,2,3,4-tetrahydro-1-naphthalenol (IV) was obtained after column chromatography with silica gel using chloroform as eluent.

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