Реакция #43453

Уравнение реакции

(2,5-dioxo-2,5-dihydro-3-furanyl)acetic acid

hydrazine sulphate

→

solid

Выход 85.4%

(3,6-Dioxo-1,2,3,6-tetrahydro-4-pyridazinyl)acetic acid

Выход 85.4%

Растворители

water

Условия реакции

Обработка

1. 1
   Температураwas heated
2. 2
   Температураto reflux for 4 hours
3. 3
   ФильтрацияThe precipitate was filtered
4. 4
   Промывкаwashing with water
5. 5
   ДругоеDrying in vacuo

Методика

A mixture of (2,5-dioxo-2,5-dihydro-3-furanyl)acetic acid (9 g) and hydrazine sulphate (7.2 g) in water was heated to reflux for 4 hours then allowed to cool to ambient temperature. The precipitate was filtered, washing with water then acetone. Drying in vacuo afforded a white solid (8.04 g, 82%).

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