Реакция #4334

Уравнение реакции

2,4,5-trichloronitrobenzene

ethylenediamine

ethanol

→

4,5-dichloro-2-nitro-N-β-aminoethylaniline

Растворители

water

Условия реакции

Обработка

1. 1
   ТемператураAfter heating
2. 2
   Температураunder reflux for 1 h 30 min
3. 3
   Температураthe reaction mixture is cooled
4. 4
   ДругоеAfter dilution with iced water, the expected product precipitates
5. 5
   Другоеmelts as 84° C.-87° C.

Методика

0.13 mole (30.6 g) of 2,4,5-trichloronitrobenzene is added to a solution of 78 g of ethylenediamine in 100 ml of 96° ethanol and 117 ml of water. After heating under reflux for 1 h 30 min, the reaction mixture is cooled. After dilution with iced water, the expected product precipitates. It melts as 84° C.-87° C.

Источник