Реакция #431467

Уравнение реакции

4-(tert-Butoxycarbonylaminomethyl)piperidine

4-ethylenedioxy-4-(4-methoxyphenyl)butyl chloride

potassium carbonate

→

1-(4-ethylenedioxy-4-(4-methoxyphenyl)butyl)-4-(tert-butoxycarbonylaminomethyl)piperidine

Выход 37.7%

Условия реакции

Обработка

1. 1
   workup.ADDITIONtreated in the same manner as in Preparation Example 181

Методика

4-(tert-Butoxycarbonylaminomethyl)piperidine (10.0 g) as a starting compound, 4-ethylenedioxy-4-(4-methoxyphenyl)butyl chloride (12.0 g) and potassium carbonate (19.3 g) were reacted and treated in the same manner as in Preparation Example 181 to give 7.65 g of 1-(4-ethylenedioxy-4-(4-methoxyphenyl)butyl)-4-(tert-butoxycarbonylaminomethyl)piperidine.

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