Реакция #42890

ord-dfa3c45841c044c79e13a902739fee12

Уравнение реакции

COC(=O)c1cscc1NC(=O)C(C)Cl
rac-4-(2-chloro-propionylamino)-thiophene-3-carboxylic acid methyl ester
Oc1ccc(Cl)c(Cl)c1
3,4-dichlorophenol
→
CC(Oc1ccc(Cl)c(Cl)c1)C(=O)Nc1cscc1C(=O)O
title compound
CC(Oc1ccc(Cl)c(Cl)c1)C(=O)Nc1cscc1C(=O)O
rac-4[-2-(3,4-Dichloro-phenoxy)-propionylamino]-thiophene-3-carboxylic acid

Реактанты

COC(=O)c1cscc1NC(=O)C(C)Cl
rac-4-(2-chloro-propionylamino)-thiophene-3-carboxylic acid methyl ester
Oc1ccc(Cl)c(Cl)c1
3,4-dichlorophenol

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

In analogy to Example 2, the title compound was prepared using rac-4-(2-chloro-propionylamino)-thiophene-3-carboxylic acid methyl ester and 3,4-dichlorophenol. MS (m/e): 360.0 (M−H).

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US07732452B2uspto-grants-2010_06